| May 2004 present | Team leader, EMBL Heidelberg |
| Feb. 2003 May 2004 | Consultant to LION bioscience AG |
| Oct. 2001 Feb. 2003 | Chief Information Officer, LION bioscience AG, Heidelberg, Germany |
| Oct. 1999 Feb. 2003 | Chief Executive Officer, LION bioscience Research Inc., Cambridge, USA |
| Oct. 1999 Oct. 2001 | Chief Executive Officer, LION bioscience Inc., Cambridge, USA |
| Mar. 1997 Dec. 1999 | Co-founder and Vice-president, Bioinformatics, LION bioscience AG in Heidelberg, Germany |
| 1994 - 1997 | Postdoctoral fellow at the EMBL - Heidelberg |
| 1990 - 1994 | PhD thesis at the EMBL-Heidelberg, supervised by Prof. K Holmes (MPIfMF, Heidelberg), Prof. A. Lesk (Cambridge, UK) and Dr. C. Sander (EMBL-Heidelberg). Title: Sequence and sequence-structure comparisons and their use for the structural and functional prediction of proteins. (Sequenz und Sequenz-Struktur Vergleiche und deren Anwendung für die Struktur- und Funktionsvorhersage von Proteinen) |
| 1988 - 1989 | Diploma thesis (master equivalent) at the EMBL-Heidelberg, supervised by Prof. K. Holmes (MPIfMF, Heidelberg) and Dr. C. Sander (EMBL-Heidelberg). Title: Secondary structure prediction of proteins using tertiary structure aspects. (Sekundärstrukturvorhersage von Proteinen unter Berücksichtigung von Tertiärstrukturaspekten) |
| 1981 1989 | Biology studies at the RWTH Aachen and University Heidelberg; During that time assistant in the Institute for Medicine at the Nuclear Research Center (Jülich, Germany). |
| Other activities | |
| Dec. 2008 present | Treasurer of the ISCB; http://www.iscb.org/ |
| Jan. 2006 present | Vice-President of the ISCB; http://www.iscb.org/ |
| Jan. 2005 present | Board member of the ISCB; http://www.iscb.org/ |
| May 2001 Oct. 2005 | Member of the supervisory board (Aufsichtsrat) of ACE bio-sciences A/S, Odense, Denmark; http://www.acebiosciences.com/ |
| Aug. 2002 Dec. 2004 | Member of the Advisory Editorial Board for BioSilico, Innovations in Computational Drug Discovery (A Drug Discovery Today Publication); http://www.drugdiscoverytoday.com |
| Feb. 2003 Dec. 2004 | Member of the Scientific Advisory Board for LION bioscience AG |